Hjem Avdelinger og ansatte Arbeidsmiljøtoksiko[..] Shan Narui

Shan Narui

Avdelingsdirektør/ledende seniorforsker – Arbeidsmiljøtoksikologi

+47 23 19 52 84

shan, narui / stami, no

Prosjektleder i prosjekter

NanoBioReal – nanomaterialer og helseeffekter

2020 – 2022 • Laura Maria Azzurra Camassa • Shan Narui
Generering, beskyttelse fra og helseeffekter av støv i nano-størrelse i smelteverksindustrien (DEMASKUS)

2016 – 2018 • Shan Narui
Polymorfier i gener knyttet til omsetning av gentoksiske stoffer og betennelsesreaksjoner og deres betydning for helserisiko

2006 – 2015 • Shan Narui
Nasjonalt (norsk) initiativ for utvikling av en felles tilnærming for regulatorisk testing av syntetiske nanomaterialer

2014 – 2019 • Shan Narui
NANOREG-EU prosjektet

2013 – 2018 • Shan Narui
Karakterisering av gen-varianter i inflammasjonsgener assosiert med lungekreftrisiko

2012 – 2016 • Shan Narui
Inflammatoriske og kreftfremkallende effekter av karbonnanonrør

2011 – 2015 • Shan Narui
Epigenetiske endringer i sentrale døgnrytme, melatonin, kjønnshormon reseptorer og deres betydning for brystkreftrisiko i norske sykepleiere

2013 – 2018 • Shan Narui

Prosjektdeltaker

NANO2FILM – Trygg nanoteknologi mot antibiotikaresistente bakterier

2025 – 2028 • Anani K. Johnny Afanou
Integrerte testmetoder for gentoksisitet

2022 – 2026 • Lina Wik
Utvikling av in vitro metoder for risikovurdering for hudsensibilisering ved blandingseksponering for irritanter og allergener – SKINSENMIX

2024 – 2028 • Jose Hernán Alfonso • Steen Mollerup
Eksponering for potensielt skadelige legemidler (cytostatika) blant sykehusansatte

2024 – 2026 • Johanna Samulin-Erdem
Cellemodell av leveren for bruk i risikovurdering av kjemikalier i arbeidsmiljøet

2022 – 2026 • Lina Wik
nanoPASS – utvikling av nye metoder for risikovurdering av nanopartikler

2023 – 2026 • Johanna Samulin-Erdem
Nanopartikler i medisinsk utstyr og arbeidstakernes helse (Safe-n-Medtech)

2019 – 2023 • Aurora Moen
PARC – Partnership for Assessment of Risk of Chemicals

2022 – 2029 • Steen Mollerup
Utvikling av realistiske metodar for testing og risikovurdering av nanomaterialar (PATROLS)

2020 – 2021 • Johanna Samulin-Erdem
Interaksjonar mellom immunceller og partiklar i utviklinga av lungerelaterte helseplager (PartiCell)

2019 – 2025 • Johanna Samulin-Erdem
Helseeffektar av nanocellulose – immunceller si rolle i utviklinga av betennelsesreaksjonar i lungene

2017 – 2021 • Johanna Samulin-Erdem
Nano-Cancer: Kreftframkallande effektar av fabrikerte nanopartiklar

2018 – 2022 • Mayes Alswady-Hoff
Plastics Fate and effects in the human body

2021 – 2025 • Anani K. Johnny Afanou
Partikkeleksponering i tannklinikker (Dentex)

2017 – 2026 • Lina Wik
Arbeid og helse i aluminiumsindustrien

2020 – 2040 • Jenny-Anne Sigstad Lie
EPHOR – Exposome Project for Health and Occupational Research

2020 – 2025 • Johanna Samulin-Erdem
Hudproblemer hos arbeidere som håndterer oljeboringsavfall

2017 – 2022 • Jose Hernán Alfonso
Etablering av et nasjonalt register for arbeidstid og helse – mulighetsstudie

2017 – 2019 • Dagfinn Matre
Kvartseksponering og lungefunksjon – Follobanen

2016 – 2026 • Karl-Christian Nordby
Arbeidstidsordninger og betydningen av disse for risikovurderinger av kjemikalier

2013 – 2018 • Jenny-Anne Sigstad Lie

Publikasjoner

Germline HLA heterozygosity is associated with decreased lung cancer risk

2026 • Human Genetics and G[..]
Circadian rhythm disruption in cardiovascular disease: a systematic review and meta-analysis...

2026 • BMC Medicine.
Organ-specific in vitro models for prediction of hazard assessment of nanomaterials

2026 • Toxicology in Vitro,[..]
Microplastics amplify the pro-inflammatory response to fungal mycelial fragments and spores ...

2026 • Frontiers in Toxicol[..]
In silico temporal mapping of fibrogenic and immune gene dynamics in rat lung following crys...

2026 • NanoImpact, 41.
Genes associated with genetic and rare lung diseases and the risk of lung cancer

2026 • BMC Cancer, 26(1).
Activation of Toll-like receptor 2 reveals microbial contamination beyond endotoxins on micr...

2025 • Toxicology in Vitro,[..]
Detection of Microbial Contamination in Nanomaterials Using LAL, rFC and Cell-Based Assays: ...

2025 • Nanomaterials, 15(24[..]
Characterization of occupational exposure to airborne particles and bioaerosols in dental cl...

2025 • Annals of Work Expos[..]
Stratifying lung adenocarcinoma risk with multi-ancestry polygenic risk scores in East Asian...

2025 • Journal of the Natio[..]
Genome-wide association study for lung cancer in 6531 African Americans reveals new suscepti...

2025 • Human Molecular Gene[..]
Pulmonary hazards of nanoplastic particles: a study using polystyrene in in vitro models of ...

2025 • Journal of Nanobiote[..]
Night shift work and indicators of cardiovascular risk: A systematic review and meta-analysis

2025 • Environmental Resear[..]
Effects of the combined exposure to chemicals and unusual working hours

2024 • Annals of Work Expos[..]
Pro-inflammatory and genotoxic responses by metal oxide nanomaterials in alveolar epithelial...

2024 • Toxicology in Vitro,[..]
Toward Standardization of a Lung New Approach Model for Toxicity Testing of Nanomaterials

2024 • Nanomaterials, 14(23).
Particulate matter constituents trigger the formation of extracellular amyloid β and Tau -co...

2024 • Nanotoxicology, 18(4[..]
Impact of individual level uncertainty of lung cancer polygenic risk score (PRS) on risk str...

2024 • Genome Medicine, 16([..]
Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies

2024 • Cancer Epidemiology,[..]
Interlaboratory comparison of endotoxin contamination assessment of nanomaterials

2024 • Nanoscale, 45.
Inflammation related to inhalation of nano and micron sized iron oxides: a systematic review

2024 • Nanotoxicology, 18(6[..]
Systematic review of mechanistic evidence for TiO2 nanoparticle-induced lung carcinogenicity

2024 • Nanotoxicology, 18(5[..]
Identification of genetically predicted DNA methylation markers associated with non–small ce...

2023 • Cancer, 130(6): 913-[..]
Candidate pathway analysis of surfactant proteins identifies CTSH and SFTA2 that influences ...

2023 • Human Molecular Gene[..]
High aspect ratio nanomaterial-induced macrophage polarization is mediated by changes in miR...

2023 • Frontiers in Immunol[..]
Chrono-modulated effects of external stressors on oxidative stress and damage in humans: A s...

2023 • Environment Internat[..]
CYP2A6 Activity and Cigarette Consumption Interact in Smoking-Related Lung Cancer Susceptibi...

2023 • Cancer Research, 84([..]
Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a Euro...

2023 • Nature Communication[..]
Mosaic Chromosomal Alterations Are Associated With Increased Lung Cancer Risk: Insight From ...

2023 • Journal of Thoracic [..]
Transferability and reproducibility of exposed air-liquid interface co-culture lung models

2023 • NanoImpact, 31.
Characterization of the internal working-life exposome using minimally and non-invasive samp...

2023 • Environmental Resear[..]
Iam hiQ – a novel pair of accuracy indices for imputed genotypes

2022 • BMC Bioinformatics, [..]
Gene–gene interaction of AhRwith and within the Wntcascade afects susceptibility to lung cancer

2022 • European Journal of [..]
Multiwalled Carbon Nanotubes Induce Fibrosis and Telomere Length Alterations

2022 • International Journa[..]
Advanced Respiratory Models for Hazard Assessment of Nanomaterials—Performance of Mono-, Co-...

2022 • Nanomaterials, 12(15).
Genome-wide interaction analysis identified low-frequency variants with sex disparity in lun...

2022 • Human Molecular Gene[..]
The Leucocyte Telomere Length, GSTM1 and GSTT1 Null Genotypes and the Risk of Chronic Obstru...

2022 • Current Issues in Mo[..]
An inter-laboratory effort to harmonize the cell-delivered in vitro dose of aerosolized mate...

2022 • NanoImpact, 28.
Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new...

2022 • Nature Genetics, 54([..]
A Large-Scale Genome-Wide Gene-Gene Interaction Study of Lung Cancer Susceptibility in Europ...

2022 • Journal of Thoracic [..]
Nano- and microplastics: a comprehensive review on their exposure routes, translocation, and...

2022 • NanoImpact.
Characterization and toxicity evaluation of air-borne particles released by grinding from tw...

2021 • Dental Materials, 37[..]
Long-Term Exposure to Nanosized TiO2 Triggers Stress Responses and Cell Death Pathways in Pu...

2021 • International Journa[..]
In vitro-in vivo correlations of pulmonary inflammogenicity and genotoxicity of MWCNT

2021 • Particle and Fibre T[..]
Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squ...

2021 • PLoS Genetics, 17(3).
The leukocyte telomere length, single nucleotide polymorphisms near TERC gene and risk of COPD

2021 • PeerJ, 9.
Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model

2021 • Cancer Research, 81([..]
Association Analysis of Driver Gene-Related Genetic Variants Identified Novel Lung Cancer Su...

2020 • Cancer Epidemiology,[..]
Causal relationships between body mass index, smoking and lung cancer. Univariable and multi...

2020 • International Journa[..]
Protein-altering germline mutations implicate novel genes related to lung cancer development

2020 • Nature Communication[..]
Effects of mild steel welding fume particles on pulmonary epithelial inflammation and endoth...

2020 • Toxicology and indus[..]
MTNR1A Promoter Methylation is Associated with Increased Breast Cancer Risk

2020 • Journal of Cancer Sc[..]
A new efficient method to detect genetic interactions for lung cancer GWAS

2020 • BMC Medical Genomics[..]
Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung ca...

2020 • Nature Communication[..]
Comprehensive functional annotation of susceptibility variants identifies genetic heterogene...

2020 • Frontiers in Medicine.
A human relevant mixture of persistent organic pollutants (POPs) and perfluorooctane sulfoni...

2020 • Toxicology Letters, [..]
Cellulose nanocrystals modulate alveolar macrophage phenotype and phagocytic function

2019 • Biomaterials, 203: 3[..]
Transcriptome-wide association study reveals candidate causal genes for lung cancer

2019 • International Journa[..]
Shared heritability and functional enrichment across six solid cancers

2019 • Nature Communication[..]
Mechanisms of Toxicity of Industrially Relevant Silicomanganese Dust on Human 1321N1 Astrocy...

2019 • International Journa[..]
Elevated platelet count appears to be causally associated with increased risk of lung cancer...

2019 • Cancer Epidemiology,[..]
Genome-wide association study of INDELs identified four novel susceptibility loci associated...

2019 • International Journa[..]
Lung cancer risk in never smokers of European descent is associated with genetic variation i...

2019 • Journal of Thoracic [..]
Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two no...

2019 • Carcinogenesis, 40(3[..]
Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networ...

2019 • OncoTarget, 10(19): [..]
Cellular Responses of Industrially Relevant Silica Dust on Human Glial Cells In Vitro

2019 • International Journa[..]
Mendelian randomization and mediation analysis of leukocyte telomere length and risk of lung...

2018 • International Journa[..]
Genetic modifiers of radon-induced lung cancer risk. A genome-wide interaction study in form...

2018 • International Archiv[..]
Circadian gene methylation in rotating-shift nurses: a cross-sectional study

2018 • Chronobiology Intern[..]
Sleep quality and methylation status of selected tumor suppressor genes among nurses and mid...

2018 • Chronobiology Intern[..]
Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethn...

2018 • Nature Communication[..]
Decreased macrophage phagocytic function due to xenobiotic exposures in vitro, difference in...

2018 • Food and Chemical To[..]
Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lu...

2018 • Nature Communication[..]
Inflammation in the pleural cavity following injection of multi-walled carbon nanotubes is d...

2018 • Nanotoxicology, 12(6[..]
Characterization of the proteome and lipidome profiles of human lung cells after low dose an...

2018 • Nanotoxicology, 12(2[..]
Criteria for grouping of manufactured nanomaterials to facilitate hazard and risk assessment...

2018 • Regulatory Toxicolog[..]
Cellular responses of human astrocytoma cells to dust from the Acheson process. An in vitro ...

2018 • Neurotoxicology, 65:[..]
Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Cau...

2017 • Carcinogenesis, 39(3[..]
Mechanisms of breast cancer in shift workers: DNA methylation in five core circadian genes i...

2017 • Journal of Cancer, 8[..]
Sleep quality and methylation status of core circadian rhythm genes among nurses and midwives

2017 • Chronobiology Intern[..]
Large-scale association analysis identifies new lung cancer susceptibility loci and heteroge...

2017 • Nature Genetics, 49([..]
Effects on human bronchial epithelial cells following low-dose chronic exposure to nanomater...

2017 • Toxicology in Vitro,[..]
Copy number variation, increased gene expression, and molecular mechanisms of neurofascin in...

2017 • Molecular Carcinogen[..]
Mechanisms of breast cancer risk in shift workers. Association of telomere shortening with t...

2017 • Cancer Medicine, 6(8[..]
Rotating night work, lifestyle factors, obesity and promoter methylation in BRCA1 and BRCA2 ...

2017 • PLOS ONE, 12(6).
Loss of MKK3 and MK2 copy numbers in non-small cell lung cancer

2016 • Journal of Cancer, 7[..]
Effects of carbon nanotubes on intercellular communication and involvement of IL-1 genes

2016 • Journal of cell comm[..]
In vitro genotoxicity testing of four reference metal nanomaterials, titanium dioxide, zinc ...

2016 • Mutagenesis, 32(1): [..]
A rare missense mutation in CHRNA4 associates with smoking behavior and its consequences

2016 • Molecular Psychiatry[..]
Genetic risk can be decreased. Quitting smoking decreases and delays lung cancer for smokers...

2016 • EBioMedicine, 11: 21[..]
Mutations in TP53 increase the risk of SOX2 copy number alterations and silencing of TP53 re...

2016 • BMC Cancer, 16(1).
Night shift work and other determinants of estradiol, testosterone, and dehydroepiandrostero...

2016 • Scandinavian Journal[..]
Association of the FAM46A gene VNTRs and BAG6 rs3117582 SNP with non small cell lung cancer ...

2015 • PLOS ONE, 10(4).
Involvement of IL-1 genes in the cellular responses to carbon nanotube exposure

2015 • Cytokine, 73(1): 128[..]
CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis—A m...

2015 • Journal of the Natio[..]
CTCF mediates the TERT enhancer-promoter interactions in lung cancer cells: Identification o...

2014 • International Journa[..]
Breast Cancer Among Nurses: Is the Intensity of Night Work Related to Hormone Receptor Status?

2013 • American Journal of [..]
Functional effect of polymorphisms in 15q25 locus on CHRNA5 mRNA, bulky DNA adducts and TP53...

2013 • International Journa[..]
DNA methylation at promoter regions of interleukin 1B, interleukin 6, and interleukin 8 in n...

2013 • Cancer Immunology an[..]
Analysis of polymorphisms in the circadian-related genes and breast cancer risk in Norwegian...

2013 • Breast Cancer Resear[..]
Functional analysis of a lung cancer risk haplotype in the IL1B gene regulatory region

2012 • Journal of Human Gen[..]
Informed conditioning on clinical covariates increases power in case-control association stu...

2012 • PLoS Genetics, 8(11).
Molecular characterization of a cancer-related single nucleotide polymorphism in the pro-inf...

2012 • Molecular Carcinogen[..]
Single nucleotide polymorphisms as susceptibility, prognostic, and therapeutic markers of no...

2012 • Lung Cancer, targets[..]
DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alteration...

2012 • International Journa[..]
Impact on disease development, genomic location and biological function of copy number alter...

2011 • PLOS ONE, 6(8).
Cigarette smoking increases copy number alterations in nonsmall-cell lung cancer

2011 • Proceedings of the N[..]
A combination of functional polymorphisms in the CASP8, MMP1, IL10 and SEPS1 genes affects r...

2011 • Lung Cancer, 71(2): [..]
Night Work and Breast Cancer Risk Among Norwegian Nurses: Assessment by Different Exposure M...

2011 • American Journal of [..]
Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21 : A pool...

2010 • Journal of the Natio[..]
Functional characterization of polymorphisms in the human TFPI gene

2010 • Biochemical and Biop[..]
International Lung Cancer Consortium : Coordinated association study of 10 potential lung ca...

2010 • Carcinogenesis, 31(4[..]
The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct format...

2009 • Carcinogenesis, 30(8[..]
Genome-Wide Analysis of Survival in Early-Stage Non-Small-Cell Lung Cancer

2009 • Journal of Clinical [..]
A specific interleukin-1B haplotype correlates with high levels of IL1B mRNA in the lung and...

2009 • Carcinogenesis, 30(7[..]
A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of n...

2008 • Carcinogenesis, 29(6[..]
Allele-specific induction of IL1B −31 T/C promoter polymorphism by lung carcinogens

2008 • Mutation Research. G[..]
International lung cancer consortium. Pooled analysis of sequence variants in DNA repair and...

2008 • Cancer Epidemiology,[..]

Andre ansatte i Arbeidsmiljøtoksikologi

Jose Hernán Alfonso

Overlege/ledende seniorforsker

+47 23 19 51 85

jose.alfonso@stami.no
Mayes Alswady-Hoff

Senioringeniør

+47 23 19 53 57

mayes.alswady-hoff@stami.no
Rita Bæra

Overingeniør

+47 23 19 52 86

rita.bara@stami.no
Laura Maria Azzurra Camassa

Forsker

+47 23 19 52 82

laura.camassa@stami.no
Tone Fykerud

Senioringeniør

+47 23 19 52 94

tone.fykerud@stami.no
Rubiyat E. Islam

Stipendiat

+47 23 19 52 92

Rubiyat.islam@stami.no
Helge Johnsen

Rådgiver

+47 23 19 53 14

helge.johnsen@stami.no
Peng Lei

Postdoktor

+47 23 19 52 75

peng.lei@stami.no
Steen Mollerup

Ledende seniorforsker

+47 23 19 52 97

steen.mollerup@stami.no
Frøydis Kristoffersen

Rådgiver/HMS-leder
Fang-Chin Lin

Overingeniør
Hamed Sadeghiankaffash

Overingeniør

+47 23 19 52 72

Hamed.sadeghiankaffash@stami.no
Johanna Samulin-Erdem

Seniorforsker

+47 23 19 52 74

johanna.samulin@stami.no
Graciela López Soop

Postdoktor

+47 23 19 52 89

graciela.soop@stami.no
Håkan Wallin

Rådgiver

+47 23 19 52 70

hakan.wallin@stami.no
Lina Wik

Forsker

+47 23 19 52 90

lina.wik@stami.no
Susann Wolf

Forsker

+47 23 19 52 83

susann.wolf@stami.no
Fikirte Debebe Zegeye

Overingeniør

+47 23 19 52 79

fikirte.zegeye@stami.no

Lukk