Genetiske faktorer

Genene har stor betydning for hvordan kroppen er i stand til å bearbeide potensielt farlige stoffer. Noen blir syke ved lave mengder, mens andre tåler mer.

Publikasjoner

Circadian gene methylation in rotating-shift nurses: a cross-sectional study

Investigating the methylation status of the circadian genes may contribute to a better understanding of the shift work-related circadian ...

Reszka, Edyta; Wieczorek, Edyta; Przybek, Monika; Jablonska, Ewa; Kaluzny, Pawel; Bukowska-Damska, Agnieszka; Zienolddiny, Shanbeh; Peplonska, Beata

Publikasjoner

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

Although several lung cancer susceptibility loci have been identified, much of the heritability for lung cancer remains unexplained. Here...

McKay, James D; Hung, Rayjean J; Han, Younghun; Zong, Xuchen; Carreras-Torres, Robert; Christiani, David C; Caporaso, Neil E; Johansson, Mattias; Xiao, Xiangjun; Li, Yafang; Byun, Jinyoung ...

Publikasjoner

Genetic predictors of recovery in low back and lumbar radicular pain

Previous data suggest that persistent back pain may be associated with genetic variability. In this study, we assessed the correlation be...

Bjorland, Siri; Røe, Cecilie; Moen, Aurora Lie; Schistad, Ellina Iordanova; Aqsa, Mahmood; Gjerstad, Johannes

Publikasjoner

A Two-Gene Prognostic Classifier for Early-Stage Lung Squamous Cell Carcinoma in Multiple Large-Scale and Geographically Diverse Cohorts

Introduction: There are no validated molecular methods that prospectively identify patients with surgically resected lung squamous cell c...

Noro, Rintaro; Ishigame, Teruhide; Walsh, Naomi; Shiraishi, Kouya; Robles, Ana I.; Ryan, Bríd M.; Schetter, Aaron J.; Bowman, Elise D.; Welsh, Judith A.; Seike, Masahiro; Gemma, Akihiko ...

Publikasjoner

Genetic risk can be decreased. Quitting smoking decreases and delays lung cancer for smokers with high and low CHRNA5 risk genotypes. A meta-analysis

Background: Recent meta-analyses show that individuals with high risk variants in CHRNA5 on chromosome 15q25 are likely to develop lung c...

Chen, Li-Shiun; Baker, Timothy; Hung, Rayjean J.; Horton, Amy; Culverhouse, Robert; Hartz, Sarah; Saccone, Nancy; Cheng, Iona; Deng, Bo; Han, Younghun; Hansen, Helen M. ...

Publikasjoner

Genetic variation in catechol-O-methyltransferase modifies effects of clonidine treatment in chronic fatigue syndrome

Clonidine, an α2-adrenergic receptor agonist, decreases circulating norepinephrine and epinephrine, attenuating sympathetic activity. Alt...

Hall, Karhryn T.; Kossowsky, Joe; Oberlander, Tim F.; Kaptchuk, Ted J.; Saul, J. Philip; Wyller, Vegard Bruun; Fagermoen, Frode Even; Sulheim, Dag; Gjerstad, Johannes; Winger, Anette; Mukamal, Kenneth Jay

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