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Lung cancer is largely an environmentally caused disease with poor prognosis. An in vitro transformation model of human bronchial epithel...
Bersaas, Audun Trygge Haugen; Arnoldussen, Yke Jildouw; Sjøberg, Mari; Haugen, Aage; Mollerup, Steen Kristen
Identification of genetic alterations in members of the p38 mitogen-activated protein kinase (MAPK) pathway is important as these protein...
Samulin-Erdem, Johanna Maria; Skaug, Vidar; Haugen, Aage; Zienolddiny, Shanbeh
Background: Amplifications of the transcription factor, SRY (sex determining region Y)-box 2 (SOX2), are common in non-small cell lung ca...
Samulin-Erdem, Johanna Maria; Skaug, Vidar; Bakke, Per S.; Gulsvik, Amund; Haugen, Aage; Zienolddiny, Shanbeh
OBJECTIVE: Impaired awareness of hypoglycemia (IAH) is a risk factor for severe hypoglycemia in people with insulin-treated diabetes; aut...
Olsen, Sandra Elise; Bjørgaas, Marit Ragnhild Rokne; Åsvold, Bjørn Olav; Sand, Trond; Stjern, Marit; Frier, Brian; Nilsen, Kristian Bernhard
Earlier studies have shown that genetic variability in the SLC6A4 gene encoding the serotonin transporter (5-HTT) may be important for th...
Meyer, Benedicte; Nguyen, Chinh Bkrong Thi Thuy; Moen, Aurora; Fagermoen, Frode Even; Sulheim, Dag; Nilsen, Hilde; Wyller, Vegard Bruun; Gjerstad, Johannes
Introduction: Up to 30% stage I lung cancer patients suffer recurrence within 5 years of curative surgery. We sought to improve existing ...
Robles, Ana I.; Arai, Eri; Mathé, Ewy A.; Okayama, Hirokazu; Schetter, Aaron J.; Brown, Derek; Petersen, David; Bowman, Elise D.; Noro, Rintaro; Welsh, Judith A.; Edelman, Daniel C. ...
Background: Chronic Fatigue Syndrome (CFS) is a common and disabling condition in adolescence with few treatment options. A central featu...
Fahmideh, Maral Adel; Lavebratt, Catharina; Schüz, Joachim; Röösli, Martin; Tynes, Tore; Grotzer, Michael; Johansen, Christoffer; Kuehni, Claudia E.; Lannering, Birgitta; Prochazka, Michaela; Schmidt, Lisbeth S. ...
The grass parasitic fungus Claviceps purpurea sensu lato produces sclerotia with toxic indole alkaloids. It constitutes several genetic g...
Negård, Mariell; Uhlig, Silvio; Kauserud, Håvard; Andersen, Tom; Høiland, Klaus; Vrålstad, Trude
Background: Recent meta-analyses show strong evidence of associations among genetic variants in CHRNA5 on chromosome 15q25, smoking quant...
Chen, Li-Shiun; Hung, Rayjean J.; Baker, Timothy B.; Horton, Amy; Culverhouse, Rob; Saccone, Nancy; Cheng, Iona; Deng, Bo; Han, Younghun; Hansen, Helen M.; Horsman, Janet ...
The interleukin-1 (IL-1) family has been implicated in cellular responses to nanoparticles including carbon nanotubes (CNTs). IL-1α and β...
Arnoldussen, Yke Jildouw; Skogstad, Asbjørn; Skaug, Vidar; Kasem, Mayes; Haugen, Aage; Benker, Nathalie; Weinbruch, Stephan; Apte, Ron N.; Zienolddiny, Shanbeh
Earlier studies indicate that lumbar radicular pain after disc herniation may be associated with a local inflammation induced by leakage ...
Pedersen, Linda Margareth; Schistad, Ellina Iordanova; Jacobsen, Line Melå; Røe, Cecilie; Gjerstad, Johannes
Sårbarhet for å utvikle sykdom etter kjemisk eksponering varierer fra individ til individ. En slik variasjon i sårbarhet har ofte sammenh...
The tumour suppressor gene TP53 is mutated in more than 50 % of human tumours, making it one of the most important cancer genes. We have ...
Wohak, Laura E.; Krais, Annette M.; Kucab, Jill E.; Stertmann, Julia; Øvrebø, Steinar; Seidel, Albrecht; Phillips, David H.; Arlt, Volker M.
Røyking er den viktigste enkelte etiologiske faktor for lungekreft, men det er estimert at opp mot 18 % av lungekrefttilfeller kan tilskr...
Studien av normal genetisk variasjon er viktig for å forstå genetisk-betinget følsomhet for sykdom. Den normale variasjonen kan være bakg...
Både epidemiologiske og eksperimentelle studier har vist at luftforurensning er assosiert med økt risiko for å utvikle lungesykdommer som...
Brystkreft utgjer 22,8% av alle krefttilfelle og er den vanlegaste kreftforma på verdsbasis. Dei siste åra har den mogelege påverknaden a...
The purpose of the proposed project is to examine the interaction between genetics, MRI findings, gender, and work factors with regard to...
We analyzed for associations between a variable number of tandem repeat (VNTR) polymorphism in the Family with sequence similarity 46, me...
Etokebe, Godfrey; Zienolddiny, Shanbeh; Kupanovac, Zeljko; Enersen, Morten; Balen, Sanja; Flego, Velkjo; Bulat-Kardum, Ljiljana; Radojčić-Badovinac, Anđelka; Skaug, Vidar; Bakke, Per S.; Haugen, Aage ...
Purpose: Lung cancer, of which 85% is non–small-cell (NSCLC), is the leading cause of cancer-related death in the United States. We used ...
Huang, Yen-Tsung; Heist, Rebecca S:; Chirieac, Lucien R.; Lin, Xihong; Skaug, Vidar; Zienolddiny, Shanbeh; Haugen, Aage; Wu, Michael C.; Wang, Zhaoxi; Su, Li; Asomaning, Kofi ...
The association of the fibroblast growth factor receptor 4 (FGFR4) Gly388Arg polymorphism with clinical stage and overall survival in a s...
Falvella, Felicia S.; Frullanti, Elisa; Galvan, Antonella; Spinola, Monica; Noci, Sara; De Cecco, Loris; Nosotti, Mario; Santambrogio, Luigi; Incarbone, Matteo; Alloisio, Marco; Calabro, Elisa ...
Background: In the present study, the influence of cytokines on 1‐year recovery in lumbar radicular pain was examined. Methods: In total,...
Iordanova, Ellina; Espeland, Ansgar; Pedersen, Lars Martin; Sandvik, Leiv; Gjerstad, Johannes; Røe, Cecilie
Previous studies indicate that lumbar radicular pain following disc herniation may be associated with release of several pro-inflammatory...
Moen, Aurora Lie; Schistad, Elina Iordanova; Rygh, Lars Jørgen; Røe, Cecilie; Gjerstad, Johannes
Objectives: Previous studies have suggested that many inflammatory cytokines, including interleukin (IL)-1a, may be associated with lumba...
Schistad, Ellina Iordanova; Jacobsen, Line Melå; Røe, Cecilie; Gjerstad, Johannes
Background: Earlier observations show that development of persistent pain may be associated with the genetic variability in the gene enco...
Hasvik, Eivind Olay; Schistad, Elina Iordanova; Grøvle, Lars; Haugen, Anne Julsrud; Røe, Cecilie; Gjerstad, Johannes