Publikasjoner

Publikasjoner • Utgivelsesår 2020

Causal relationships between body mass index, smoking and lung cancer. Univariable and multivariable Mendelian randomization

At the time of cancer diagnosis, body mass index (BMI) is inversely correlated with lung cancer risk, which may reflect reverse causality...

Wen Zhou; Geoffrey Liu; Rayjean J. Hung; Philip C. Haycock; Melinda C. Aldrich; Susanne M. Arnold; Heike Bickeböller; Stig E. Bojesen; Paul Brennan; Hans Brunnström; Olle Melander ...

Publikasjoner • Utgivelsesår 2020

Pro-inflammatory effects of crystalline- and nano-sized non-crystalline silica particles in a 3D alveolar model

Background Silica nanoparticles (SiNPs) are among the most widely manufactured and used nanoparticles. Concerns about potential health e...

Tonje Schwach Skuland; Marit Låg; Arno Gutleb; Bendik Christian Brinchmann; Tommaso Serchi; Johan Øvrevik; Jørn Andreas Holme; Magne Arnold Refsnes

Publikasjoner • Utgivelsesår 2020

How leadership behaviors influence the effects of job predictability and perceived employability on employee mental health – a multilevel, prospective study

Objectives This study aimed to elucidate the potential moderating effect of fair-, empowering-, and supportive-leadership behaviors on th...

Lise Fløvik; Stein Knardahl; Jan Olav Christensen

Publikasjoner • Utgivelsesår 2020

Perfluoroalkyl acids potentiate glutamate excitotoxicity in rat cerebellar granule neurons

Perfluoroalkyl acids (PFAAs) are persistent man-made chemicals, ubiquitous in nature and present in human samples. Although restrictions ...

Hanne Friis Berntsen; Angel Moldes-Anaya; Cesilie Granum Bjørklund; Lorenzo Ragazzi; Trude M Haug; Rønnaug Strandabø; Steven Verhaegen; Ragnhild Elisabeth Paulsen; Erik Ropstad; Andrew Tasker

Publikasjoner • Utgivelsesår 2020

Protein-altering germline mutations implicate novel genes related to lung cancer development

Few germline mutations are known to affect lung cancer risk. We performed analyses of rare variants from 39,146 individuals of European ...

Xuemei Ji; Semanti Mukherjee; Maria Teresa Landi; Yohan Bosse; Philippe Joubert; Dakai Zhu; Ivan P. Gorlov; Xiangjun Xiao; Younghun Han; Olga Gorlova; Rayjean J. Hung ...

Publikasjoner • Utgivelsesår 2020

Integration of multiomic annotation data to prioritize and characterize inflammation and immune‐related risk variants in squamous cell lung cancer

Clinical trial results have recently demonstrated that inhibiting inflammation by targeting the interleukin‐1β pathway can offer a signif...

Ryan Sun; Miao Xu; Xihao Li; Sheila Gaynor; Hufeng Zhou; Zilin Li; Yohan Bossé; Stephen Lam; Ming-Sound Tsao; Adonina Tardón; Chu Chen ...

Publikasjoner • Utgivelsesår 2020

Pulmonary function and high-resolution computed tomography in outdoor rock drillers exposed to crystalline silica

Objectives Chronic obstructive pulmonary disease and silicosis are associated with exposure to crystalline silica. We determined the expo...

Bente Ulvestad; Mariann Ulvestad; Nils Petter Skaugset; Trond M Aaløkken; Anne Günther; Thomas Clemm; May Brit Samersaw-Lund; Dag Ellingsen

Publikasjoner • Utgivelsesår 2020

The association between selected genetic variants and individual differences in experimental pain

Objectives The underlying mechanisms for individual differences in experimental pain are not fully understood, but genetic susceptibilit...

Marie Lie; Bendik Winsvold; Johannes Gjerstad; Dagfinn Matre; Linda Margareth Pedersen; Ingrid Heuch; John-Anker Zwart; Kristian Bernhard Nilsen

Publikasjoner • Utgivelsesår 2020

Long-term sickness absence among young and middle-aged workers in Norway. The impact of a population-level intervention

Background The study objective was to evaluate the impact of a population-level intervention (the IA Agreement) on the of one-year risk ...

Therese Nordberg Hanvold; Petter Kristensen; Karina Corbett; Rachel Louise Hasting; Ingrid Sivesind Mehlum

Publikasjoner • Utgivelsesår 2020

Examining the lower range of the association between alcohol intake and risk of incident hospitalization with atrial fibrillation

Background Evidence is sparse on the association between alcohol intakes in the lower range and risk of atrial fibrillation (AF). We aim...

Inger Ariansen; Eirik Magnus Meek Degerud; Knut Gjesdal; Grethe S. Tell; Øyvind Næss

Publikasjoner • Utgivelsesår 2020

Do intensity of pain alone or combined with pain duration best reflect clinical signs in the neck, shoulder and upper limb?

Objectives It is important to validate self-reported musculoskeletal pain used in epidemiological studies for evaluation of pain outcome...

Kaj Bo Veiersted; Therese Nordberg Hanvold; Lars-Kristian Lunde; Markus Koch; Stein Knardahl; Morten Wærsted

Publikasjoner • Utgivelsesår 2020

Biomonitoring of the benzene metabolite s-phenylmercapturic acid and the toluene metabolite s-benzylmercapturic acid in urine from firefighters

The aim of this study was to determine firefighter’s exposure to benzene and toluene during a fire drill by monitoring air benzene and to...

Cecilie Rosting; Raymond Olsen

Publikasjoner • Utgivelsesår 2020

Work-life prevalence of self-reported occupational injuries in mothers of a birth cohort

Purpose: To study self-reported occupational injuries among mothers of a large birth cohort study and to assess the relation of their cha...

Joana Amaro; Ana Catarina Queiroga; João Amaro; Ingrid Sivesind Mehlum; Raquel Lucas

Publikasjoner • Utgivelsesår 2020

Effects of mild steel welding fume particles on pulmonary epithelial inflammation and endothelial activation

Welders have an increased risk for cardiovascular disease (CVD) following exposure to welding fumes. The underlying mechanisms are largel...

Johanna Maria Samulin-Erdem; Yke Jildouw Arnoldussen; Sepideh Tajik; Dag Ellingsen; Shanbeh Zienolddiny

Publikasjoner • Utgivelsesår 2020

Pro-inflammatory role of AQP4 in mice subjected to intrastriatal injections of the Parkinsonogenic toxin MPP

Aquaporin-4 (AQP4) is critically involved in brain water and volume homeostasis and has been implicated in a wide range of pathological c...

Agnete Prydz; Katja Stahl; Soulmaz Rahmani; Nadia Skauli; Øivind Skare; Ole Petter Ottersen; Mahmood Amiry-Moghaddam

Publikasjoner • Utgivelsesår 2020

MTNR1A Promoter Methylation is Associated with Increased Breast Cancer Risk

Shift work, particularly, night work has been classified as a probable carcinogen to humans based on the increased risk observed in epi...

Johanna Maria Samulin-Erdem; Øivind Skare; Marte Petersen-Øverleir; Heidi Ødegaard Notø; Jenny-Anne Sigstad Lie; Kristina Kjærheim; Edyta Reszka; Beata Pepłońska; Shanbeh Zienolddiny

Publikasjoner • Utgivelsesår 2020

Implantasjon av hjertestartere ved St. Olavs hospital 2006–15

BAKGRUNN Implantasjon av hjertestarter (implantable cardioverter defibrillator, ICD) er etablert behandling hos pasienter med høy risik...

Fred Mathias Nyman; Ina Charlotte Molaug; Anne Marte Næss; Torvald Espeland; Jan Pål Loennechen; Ole Christian Mjølstad

Publikasjoner • Utgivelsesår 2020

A new efficient method to detect genetic interactions for lung cancer GWAS

Background Genome-wide association studies (GWAS) have proven successful in predicting genetic risk of disease using single-locus models...

Jennifer Luyapan; Xuemei Ji; Siting Li; Xiangjun Xiao; Dakai Zhu; Eric J. Duell; David C. Christiani; Matthew B. Schabath; Susanne M. Arnold; Shanbeh Zienolddiny; Hans Brunnström ...

Publikasjoner • Utgivelsesår 2020

The influence of age, gender and the FKBP5 genotype on subjective health complaints in the Norwegian working population

Objective In the present study we examined the potential association between age, gender, the genetic variant FKBP5 rs9470080 and subjec...

Ann-Christin Sannes; Jan Olav Christensen; Morten Birkeland Nielsen; Johannes Gjerstad

Publikasjoner • Utgivelsesår 2020

Maternal exposure to psychosocial job strain during pregnancy and behavioral problems in the 11-year-old children. A Danish cohort study

Maternal psychosocial stress may impact child neurodevelopment, but little is known regarding psychosocial job strain. We hypothesized hi...

Camilla Sandal Sejbaek; Janni Niclasen; Jens Peter E. Bonde; Petter Kristensen; Ann Dyreborg Larsen; Vivi Schlünssen; Karin Sørig Hougaard

Publikasjoner • Utgivelsesår 2020

Better hearing in Norway. A comparison of two HUNT Cohorts 20 years apart

Objective: To obtain updated robust data on a age-specific prevalence of hearing loss in Norway and determine whether more recent birth...

Bo Lars Engdahl; Bjørn Heine Strand; Lisa Aarhus

Publikasjoner • Utgivelsesår 2020

A Case Study of Brass Foundry Workers’ Estimated Lead (Pb) Body Burden from Different Exposure Routes

Objectives The most pronounced occupational exposure routes for lead (Pb) are inhalation and gastrointestinal uptake mainly through hand...

Anneli Julander; Klara Midander; Sandra Garcia-Garcia; Per Vihlborg; Pål Graff

Publikasjoner • Utgivelsesår 2020

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

Impaired lung function is often caused by cigarette smoking, making it challenging to disentangle its role in lung cancer susceptibility....

Linda Kachuri; Mattias Johansson; Sara R. Rashkin; Rebecca E. Graff; Yohan Bossé; Venkata Manem; Neil E. Caporaso; Maria Teresa Landi; David C. Christiani; Paolo Vineis; Geoffrey Liu ...

Publikasjoner • Utgivelsesår 2020

Trace Elements in the Large Population-Based HUNT3 Survey

The Nord-Trøndelag Health Study (The HUNT Study) is a large health survey population study in the county of Trøndelag, Norway. The survey...

Tore Syversen; Lars Gjermund Evje; Susann Wolf-Grosse; Trond Peder Flaten; Syverin Lierhagen; Anica Simic

Publikasjoner • Utgivelsesår 2020

Effort‐reward imbalance at work and weight changes in anationwide cohort of workers in Denmark

Objective To investigate the relation between effort‐reward imbalance (ERI) at work and subsequent weight changes. Methods We includ...

Mads Nordentoft; Naja Hulvej Rod; Jens Peter Bonde; Jakob Bue Bjorner; Bryan Cleal; Ann Dyreborg Larsen; Ida E.H. Madsen; Linda L. Magnusson Hanson; Mette A. Nexo; Line Rosendahl Meldgaard Pedersen; Tom Sterud ...