Hjem Publikasjoner Occupation and cutaneous melanoma. A 45‐y[...]

Occupation and cutaneous melanoma. A 45‐year historical cohort study of 14.9 million people in five Nordic countries

Vit. artikkel

Publisert

  • 2020

Forskningsområde

Fysisk arbeidsmiljø

Background The age‐adjusted incidence of cutaneous melanoma (CM) in the Nordic countries has increased during the last 60 years. Few prospective population‐based studies have estimated the occupational variation in CM risk over time. Objectives To determine occupational variation in CM risk. Methods A historical prospective cohort study with a 45‐year follow‐up from 1961 to 2005 (Nordic Occupational Cancer Study, NOCCA) based on record linkages between census and cancer registry data for Nordic residents aged 30–64 years in Denmark, Finland, Iceland, Norway and Sweden. National occupational codes were converted to 53 occupational categories, and stratified into indoor, outdoor and mixed work, and into socioeconomic status. The standardized incidence ratios (SIRs) were estimated as observed number of CM cases divided by the expected number calculated from stratum‐specific person‐years and national CM incidence rates. Results During a follow‐up of 385 million person‐years, 83 898 incident cases of CM were identified. In all countries combined, men with outdoor work had a low SIR of 0·79 [95% confidence interval (CI) 0·77–0·81] and men with indoor work had a high SIR of 1·09 (95% CI 1·07–1·11). Differences in women pointed in the same direction. High socioeconomic status was associated with an excess risk: SIR 1·34 (95%...

Alfonso, Jose Hernan; Martinsen, Jan Ivar; Weiderpass, Elisabete; Pukkala, E.; Kjærheim, Kristina; Tryggvadottir, L.; Lynge, E.
British Journal of Dermatology Blackwell Science Ltd., British Journal of Dermatology
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