Hjem Publikasjoner Airway inflammation among compost workers[...]

Airway inflammation among compost workers exposed to actinomycetes spores

Objectives: To study the associations between exposure to bioaerosols and work-related symptoms, lung function and biomarkers of airway inflammation in compost workers. Material and Methods: Personal full-shift exposure measurements were performed on 47 workers employed at five windrow plants (n=20) and five reactor plants (n=27). Samples were analyzed for endotoxins, bacteria, fungal and actinomycetes spores. Health examinations were performed on workers and 37 controls before and after work on the day exposure was measured. The examinations included symptoms recorded by questionnaire, lung function by spirometry and nasal dimensions by acoustic rhinometry (AR). The pneumoproteins CC16, SP-D and SP-A were measured in a blood sample drawn at the end of the day. Results: The levels of endotoxins (median 3 EU/m3 , range 0–730 EU/m3) and actinomycetes spores (median 0.2 × 106 spores/m3, range 0–590 × 106 spores/m3) were significantly higher in reactor plants compared to windrow plants. However, windrow composting workers reported more symptoms than reactor composting workers, probably due to use of respiratory protection. Exposure-response relationships between actinomycetes spores exposure and respiratory effects, found as cough and nose irritation during a shift, was significantly increased (OR 4.3, 95% CI 1.1–16, OR 6.1, 95% CI 1.5–25, respectively, p<0.05) among workers exposed...

Heldal, Kari Emilie; Madsø, Lene; Wijnand, Eduard
AAEM: Annals of Agricultural and Environmental Medicine 22(2): 253–258
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