Publikasjoner

Biological monitoring of welders' exposure to chromium, molybdenum, tungsten and vanadium

Background Welders are exposed to a number of metallic elements during work. Bioaccessability, that is important for element uptake, has ...

Ellingsen, Dag; Chashchin, Maxim; Berlinger, Balazs; Fedorov, Vladimir; Chashchin, Valery; Thomassen, Yngvar

Association between exposure in the cement production industry and non-malignant respiratory effects: A systematic review

Objectives: Based on findings from a systematic literature search, we present and discuss the evidence for an association between exposur...

Fell, Anne Kristin Møller; Nordby, Karl-Christian

Time-dependent effects of perfluorinated compounds on viability in cerebellar granule neurons: Dependence on carbon chain length and functional group attached

The toxicity of long chained perfluoroalkyl acids (PFAAs) has previously been reported to be related to the length of the perfluorinated ...

Berntsen, Hanne Friis; Bjørklund, Cesilie Granum; Audinot, Jean-Nicolas; Hofer, Tim; Verhaegen, Steven; Lentzen, Esther; Gutleb, Arno; Ropstad, Erik

Multi-walled carbon nanotube-induced genotoxic, inflammatory and pro-fibrotic responses in mice: Investigating the mechanisms of pulmonary carcinogenesis

The International Agency for Research on Cancer has classified one type of multi-walled carbon nanotubes (MWCNTs) as possibly carcinogeni...

Rahman, Luna; Jacobsen, Nicklas Raun; Aziz, Syed Abdul; Wu, Dongmei; Williams, Andrew; Yauk, Carole L.; White, Paul; Wallin, Håkan; Vogel, Ulla; Halappanavar, Sabina

Essential and non-essential trace elements among working populations in Ghana

Background Lead battery repair workers (LBRW) and electronic repair workers (ERW) may be exposed to inorganic components during work. Thi...

Dartey, Emmanuel; Berlinger, Balazs; Weinbruch, Stephan; Thomassen, Yngvar; Odland, Jon Øyvind; Brox, Jan; Nartey, Vincent K.; Yeboah, Francis A.; Ellingsen, Dag

Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: Insights from an adverse outcome pathway framework

Background: The accumulation of MWCNTs in the lung environment leads to inflammation and the development of disease similar to pulmonary ...

Nikota, Jake; Banville, Allyson; Goodwin, Laura Rose; Wu, Dongmei; Williams, Andrew; Yauk, Carole Lynn; Wallin, Håkan; Vogel, Ulla; Halappanavar, Sabina

Parental occupational exposure to organic solvents and testicular germ cell tumors in their offspring. NORD-TEST Study

Background: Testicular germ cell tumors (TGCT) were suggested to have a prenatal environmentally related origin. The potential endocrine ...

Le Cornet, Charlotte; Fervers, Béatrice; Pukkala, Eero; Tynes, Tore; Feychting, Maria; Hansen, Johnni; Togawa, Kayo; Nordby, Karl-Christian; Dalton, Susanne Oksbjerg; Uuksulainen, Sanni; Wiebert, Pernilla ...

The design of an environmentally relevant mixture of persistent organic pollutants for use in in vivo and in vitro studies

Amongst the substances listed as persistent organic pollutants (POP) under the Stockholm Convention on Persistent Organic Pollutants (SCP...

Berntsen, Hanne Friis; Berg, Vidar; Thomsen, Cathrine; Ropstad, Erik; Zimmer, Karin Elisabeth

Copy number variation, increased gene expression, and molecular mechanisms of neurofascin in lung cancer

Metastasis and cell adhesion are key aspects of cancer progression. Neurofascin (NFASC) is a member of the immunoglobulin superfamily of ...

Samulin-Erdem, Johanna Maria; Arnoldussen, Yke Jildouw; Skaug, Vidar; Haugen, Aage; Zienolddiny, Shanbeh

Comparison of air samplers for determination of isocyanic acid and applicability for work environment exposure assessment

Isocyanic acid (ICA) is one of the most abundant isocyanates formed during thermal decomposition of polyurethane (PUR), and other nitroge...

Jankowski, Mikolaj Jan; Olsen, Raymond; Thomassen, Yngvar; Molander, Pål

Maternal exposure to a mixture of persistent organic pollutants (POPs) affects testis histology, epididymal sperm count and induces sperm DNA fragmentation in mice

Persistent organic pollutants (POPs) are widespread throughout the environment and some are suspected to induce reproductive toxicity. As...

Khezri, Abdolrahman; Lindeman, Birgitte; Krogenæs, Anette Kristine; Berntsen, Hanne Friis; Zimmer, Karin Elisabeth; Ropstad, Erik

Effects on human bronchial epithelial cells following low-dose chronic exposure to nanomaterials: A 6-month transformation study

The most plausible exposure route to manufactured nanomaterials (MNM) remains pulmonary inhalation. Yet, few studies have attempted to as...

Phuyal, Santosh; Kasem, Mayes; Rubio, Laura; Karlsson, Hanna; Marcos, Ricard; Skaug, Vidar; Zienolddiny, Shanbeh

Differences in inflammation and acute phase response but similar genotoxicity in mice following pulmonary exposure to graphene oxide and reduced graphene oxide

We investigated toxicity of 2–3 layered >1 μm sized graphene oxide (GO) and reduced graphene oxide (rGO) in mice following single intratr...

Bengtson, Stefan; Knudsen, Kristina B.; Kyjovska, Zdenka O.; Berthing, Trine; Skaug, Vidar; Levin, Marcus; Koponen, Ismo K.; Shivayogimath, Abhay; Booth, Timothy J.; Alonso, Beatriz; Pesquera, Amaia ...

Source identification of individual soot agglomerates in Arctic air by transmission electron microscopy

Individual soot agglomerates collected at four different locations on the Arctic archipelago Svalbard (Norway) were characterised by tran...

Weinbruch, Stephan; Benker, Natalie; Kandler, Konrad; Schütze, Katharina; Kling, Katharina; Berlinger, Balazs; Thomassen, Yngvar; Drotikova, Tatiana Mikhailovna; Kallenborn, Roland

The fungal neurotoxin penitrem A induces the production of reactive oxygen species in human neutrophils at submicromolar concentrations

Penitrem A is a fungal neurotoxin that recurrently causes intoxication in animals, and occasionally also in humans. We have previously re...

Berntsen, Hanne Friis; Bogen, Inger Lise; Wigestrand, Mattis B; Fonnum, Frode; Walaas, S. Ivar; Moldes-Anaya, Angel

Medisinsk fødselsregister i miljøovervåkingen - muligheter og begrensninger

Overvåking har vært en prioritert oppgave for Medisinsk fødselsregister helt siden starten i 1967. Denne oversikten dekker miljøovervåkin...

Kristensen, Petter

Pulmonary function and high-resolution computed tomography examinations among offshore drill floor workers

Purpose: The aim of this study was to assess short-term changes in pulmonary function in drill floor workers currently exposed to airborn...

Kirkhus, Niels Einar; Skare, Øivind; Ulvestad, Bente; Aaløkken, Trond Mogens; Günther, Anne; Olsen, Raymond; Thomassen, Yngvar; Samersaw-Lund, May Brit; Ellingsen, Dag

WHO guidelines on protecting workers from potential risks of manufactured nanomaterials

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Influence of dispersion medium on nanomaterial-induced pulmonary inflammation and DNA strand breaks: Investigation of carbon black, carbon nanotubes and three titanium dioxide nanoparticles

Intratracheal instillation serves as a model for inhalation exposure. However, for this, materials are dispersed in appropriate media tha...

Hadrup, Niels; Bengtson, Stefan; Jacobsen, Nicklas R. ; Jackson, Petra; Nocun, Marek ; Saber, Anne T.; Jensen, Keld A. ; Wallin, Håkan; Vogel, Ulla

Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism

The tumour suppressor gene TP53 is mutated in more than 50 % of human tumours, making it one of the most important cancer genes. We have ...

Wohak, Laura E.; Krais, Annette M.; Kucab, Jill E.; Stertmann, Julia; Øvrebø, Steinar; Seidel, Albrecht; Phillips, David H.; Arlt, Volker M.

A multinational case-control study on childhood brain tumours, anthropogenic factors, birth characteristics and prenatal exposures: A validation of interview data

Little is known about the aetiology of childhood brain tumours. We investigated anthropometric factors (birth weight, length, maternal ag...

Vienneau, Danielle; Infanger, Denis; Feychting, Maria; Schüz, Joachim; Schmidt, Lisbeth Samsø; Poulsen, Aslak Harbo; Tettamanti, Giorgio; Klæboe, Lars Hind Bakken; Kuehni, Claudia E.; Tynes, Tore; Von der Weid, Nicolas ...

Carbon Nanotube Emissions from Arc Discharge Production: Classification of Particle Types with Electron Microscopy and Comparison with Direct Reading Techniques

Introduction: An increased production and use of carbon nanotubes (CNTs) is occurring worldwide. In parallel, a growing concern is emergi...

Ludvigsson, Linus; Isaxon, Christina; Nilsson, Patrik T.; Tinnerberg, Hakan; Messing, Maria E.; Rissler, Jenny; Skaug, Vidar; Gudmundsson, Anders; Bohgar, Mats; Hedmer, Maria; Pagels, Joakim

Biologisk monitorering av ovnstappere eksponert for mangan i manganlegeringsindustrien

STAMI-rapport nr. 1/2016. Statens arbeidsmiljøinstitutt har i samarbeid med ERAMET (Norge) undersøkt om bestemmelse av konsentrasjonen av...

Ellingsen, Dag G.; Berlinger, Balazs; Dahl, Kari; Thomassen, Yngvar

Pulmonary function and serum pneumoproteins in professional ski waxers

Context: Professional ski waxers are exposed to particulate matter (PM) during work, but little is known about untoward pulmonary effects...

Freberg, Baard Ingegerdsson; Olsen, Raymond; Thorud, Syvert; Daae, Hanne Line; Hersson, Merete; Molander, Pål; Barregard, Lars; Ellingsen, Dag G.

Profiling of 3-hydroxy fatty acids as environmental markers of endotoxin using liquid chromatography coupled to tandem mass spectrometry

3-Hydroxy acids are constituents of the lipid A part of lipopolysaccharides and may potentially be used as chemical markers of endotoxin....

Uhlig, Silvio; Negård, Mariell; Heldal, Kari Emilie; Straumfors, Anne; Madsø, Lene; Bakke, Berit; Wijnand, Eduard