{"id":5380,"date":"2026-07-27T12:09:55","date_gmt":"2026-07-27T10:09:55","guid":{"rendered":"https:\/\/stami.no\/en\/?post_type=project&#038;p=5380"},"modified":"2026-07-27T12:09:57","modified_gmt":"2026-07-27T10:09:57","slug":"skin-exposure-and-contact-dermatitis-among-workers-handling-oil-drilling-waste","status":"publish","type":"project","link":"https:\/\/stami.no\/en\/project\/skin-exposure-and-contact-dermatitis-among-workers-handling-oil-drilling-waste\/","title":{"rendered":"Skin Exposure and Contact Dermatitis among Workers Handling Oil Drilling Waste"},"content":{"rendered":"<div class=\"content-entry intro-text-container\">\n\t\n\n<p class=\"lead wp-block-paragraph\">Skin exposure during the handling of oil drilling waste may contribute to the development of contact dermatitis in workers. This project analyses existing data to understand the relationship between exposure and skin problems, and the findings will also be relevant for other occupational groups and for the broader understanding of eczema in the general population.<\/p>\n\n\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Project Description<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">This project investigates how working with oil drilling waste affects the skin of workers. Drilling waste contains complex mixtures of oil, chemicals, and particles that can penetrate the skin, impair the skin barrier, and contribute to the development of skin conditions such as eczema.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The project is based on an extensive dataset collected in a previous research project, which includes detailed information on occupational skin exposure, skin barrier function, and skin problems among workers. These data are analysed to assess levels of skin exposure in everyday work and how this relates to changes in skin barrier function and the development of skin problems.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The dataset includes samples collected from work gloves and skin, measurements of skin hydration, pH, and the skin\u2019s ability to retain moisture, as well as questionnaire data on skin symptoms. In addition, genetic and epigenetic analyses are included to investigate how individual differences in skin barrier function and immune response may influence susceptibility to eczema.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A key focus of the project is to understand the mechanisms underlying the development of contact dermatitis by examining the relationships between skin exposure, impairment of the skin barrier, and biological responses in the skin. An important aim is to explain why some workers develop skin problems, while others with apparently similar exposure do not. In this context, both genetic susceptibility and epigenetic changes are of particular interest. Epigenetic mechanisms, which may be influenced by occupational exposure, have been only minimally explored in occupational dermatology and represent an important emerging research area.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">By integrating exposure data, biological responses, and clinical outcomes, the project will contribute to a more precise understanding of how occupational skin exposure leads to disease, and why certain individuals are more vulnerable than others.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Occupational skin diseases are among the most common work-related health problems in Norway and Europe, and may lead to sick leave, reduced work ability, and in some cases job change or disability. At the same time, knowledge about the risks for workers handling drilling waste in Norway remains limited.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The results will be particularly relevant for Norwegian working life, where handling of drilling waste is an important part of the oil and gas industry. At the same time, the project has significant transfer value to other occupational groups with skin exposure, as the methods developed can be applied to quantify exposure and study relationships between exposure, skin barrier function, and disease in other work environments. The use of quantitative methods to assess exposure, biological mechanisms, and clinical outcomes has only to a limited extent been applied in occupational dermatology in Norway.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The knowledge generated will contribute to improved prevention through more targeted interventions, safer work practices, and improved protective equipment. It will also strengthen the basis for risk assessment in occupational health and safety and contribute to a better understanding of eczema as a common condition in the general population.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Several groups will benefit from the project:<br>\u2022 Workers, through improved protection and follow-up<br>\u2022 Employers, through improved working conditions and reduced sick leave<br>\u2022 Authorities, through a stronger evidence base for regulations and recommendations<br>\u2022 Healthcare professionals, through improved knowledge for prevention and management of occupational skin diseases, including identification of vulnerable individuals<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In the long term, the project will contribute to a safer and more sustainable working environment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Project Lead and Team<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Project Lead: Jose Hern\u00e1n Alfonso<\/li>\n\n\n\n<li>PhD Candidate: Lars Henrik Bj\u00f8rneboe<\/li>\n\n\n\n<li>Co-Supervisors: Olav Sundnes (UiO) og Shan Zienolddiny (STAMI)<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Collaborating Institutions<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Oslo University Hospital HF. International collaborators in the Netherlands and Croatia<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Funding<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Salary funding from Oslo University Hospital and STAMI. Operational funding and costs for participation in international courses and conferences are covered by STAMI.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Additional information<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The project is approved by the Regional Ethics Committee and follows applicable regulations for research ethics and data protection.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">More information is to be found on the\u00a0<a href=\"https:\/\/stami.no\/prosjekt\/hudeksponering-og-kontakteksem-hos-arbeidere-som-handterer-boreavfall-fra-oljeindustrien\/\">Norwegian project page<\/a><a href=\"https:\/\/stami.no\/prosjekt\/ephor-exposome-project-for-health-and-occupational-research\/\">.<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"show_date_option_selector":"publication_date"},"categories":[],"research-area":[26],"class_list":["post-5380","project","type-project","status-publish","hentry","research-area-chemical-and-biological-working-environment"],"acf":[],"_links":{"self":[{"href":"https:\/\/stami.no\/en\/wp-json\/wp\/v2\/project\/5380","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stami.no\/en\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/stami.no\/en\/wp-json\/wp\/v2\/types\/project"}],"wp:attachment":[{"href":"https:\/\/stami.no\/en\/wp-json\/wp\/v2\/media?parent=5380"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stami.no\/en\/wp-json\/wp\/v2\/categories?post=5380"},{"taxonomy":"research-area","embeddable":true,"href":"https:\/\/stami.no\/en\/wp-json\/wp\/v2\/research-area?post=5380"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}